Lung microvasculopathy in chronic thromboembolic pulmonary hypertension: high-resolution findings with photon-counting detector CT in 29 patients
Question Lung microvascular lesions play a crucial role in the origin of residual pulmonary hypertension after successful thromboendarterectomy, currently beyond the scope of imaging. Findings The expected morphological abnormalities at the level of distal pulmonary circulation in CTEPH were found to be depictable in each zone of mosaic perfusion. Clinical relevance This study suggests that the high-spatial resolution of PCD-CT has the capability of approaching the complex pathophysiology of small-vessel disease in CTEPH, providing important information prior to therapeutic decisions.
Authors
- Marie Delobelle
- Martine Rémy‐Jardin (ORCID: https://orcid.org/0000-0003-1944-4288)
- Thomas G. Flohr (ORCID: https://orcid.org/0000-0002-9524-5531)
- Alain Duhamel
- Jean-François Bervar
- Jacques Rémy
Institutions
- Siemens (Germany) (DE)
- École Pratique des Hautes Études (FR)
- Université de Lille (FR)
- Maastricht University Medical Centre (NL)
- Centre Hospitalier Universitaire de Lille (FR)
- Laboratoire d'Automatique, de Mécanique et d'Informatique Industrielles et Humaines (FR)
- Siemens Healthineers (Germany) (DE)
- Centre Hospitalier de Valenciennes (FR)
- Université Polytechnique Hauts-de-France (FR)
Publication Details
- Journal
- European Radiology
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1007/s00330-025-11561-w
- Citations
- 2
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.04