Blood biomarkers for brain injury in chronic subdural hematomas: postoperative dynamics and relation to long-term outcome
Surgical CSDH patients exhibit ongoing central nervous system cellular injury, demonstrated via increased fluid biomarkers for brain injury preoperatively, which immediately improved after surgery and was strongly related to long-term outcome. The extent of preoperative biomarker elevation could aid in the decision-making for surgical indication and urgency.
Authors
- Caroline Lindblad (ORCID: https://orcid.org/0000-0003-4952-8597)
- Felix Axelsson
- Kaj Blennow (ORCID: https://orcid.org/0000-0002-1890-4193)
- Teodor Svedung Wettervik (ORCID: https://orcid.org/0000-0002-4556-5721)
- Fernando González‐Ortiz (ORCID: https://orcid.org/0000-0001-7897-9456)
- Jimmy Sundblom (ORCID: https://orcid.org/0000-0001-5105-0508)
- Christine Chidiac (ORCID: https://orcid.org/0000-0003-0830-4108)
- Henrik Zetterberg
Institutions
- Uppsala University (SE)
- University of Science and Technology of China (CN)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- Sorbonne Université (FR)
- Pitié-Salpêtrière Hospital (FR)
- UK Dementia Research Institute (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- Institut du Cerveau (FR)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-04-18
- DOI
- https://doi.org/10.3171/2025.1.jns242942
- Citations
- 1
- Primary Topic
- Neurosurgical Procedures and Complications
- Type
- article
- Field-Weighted Citation Impact
- 1.39