Comparative study of immune biomarkers and oxidative stress in patients with COVID-19, dengue, and malarial infection

Dengue, a vector-borne virus-related contamination transferred by the Aedes mosquito. Malaria remains a main transferrable infection that affects billions of people, once diseased with Plasmodium organisms. The COVID-19 (coronavirus disease 2019) that took over the world in December 2019 has everlasting distressing effects on people's lives worldwide. Coronavirus infection is extremely contagious and pathogenic biological contamination produced by the severe respirational disorder coronavirus 2 (SARS-CoV-2), which affected the global epidemic. A significant decrease (P <0.05) of GSH was observed in different groups of patients with dengue and malaria, while a significant increase in COVID-19. A Significant decrease in catalase in dengue, malaria, and COVID-19 was observed. Significant results in decreasing trend of vitamin C in dengue, malaria, and COVID-19 observed. In the peripheral film, ESR in dengue patients increased by 11.62±3.85 in malarial patients by 53.52±26.14 and in COVID-19 patients it is observed at 6.70±2.91. CRP increasing trends were observed in all groups. To perform a comparative chemical analysis of patients with COVID-19, dengue, and malaria by evaluating key biochemical markers, oxidative stress parameters, and immune profiles, to identify distinctive patterns, overlapping features, and potential diagnostic or prognostic indicators associated with each infection.