Investigating the impact of landfill age and season on the occurrence and dissemination of antibiotic resistance genes in leachate and the underlying mechanisms using metagenomics
Our study provides the first systematic characterization of ARG dynamics in semi-arid landfill leachate, offering crucial insights for developing targeted strategies to mitigate ARG dissemination in these distinct ecological contexts. These findings establish a theoretical framework for understanding ARG transmission in semi-arid environments, while providing empirical evidence to inform environmental management practices.
Authors
- Guodong Kang (ORCID: https://orcid.org/0000-0001-8778-3156)
- Ning Chang (ORCID: https://orcid.org/0000-0003-2842-7658)
- Houhu Zhang (ORCID: https://orcid.org/0000-0001-6347-5765)
- Weitao Shen (ORCID: https://orcid.org/0000-0002-0794-0164)
- Shenghu Zhang (ORCID: https://orcid.org/0000-0002-7080-4528)
- Yanhua Liu (ORCID: https://orcid.org/0000-0001-7636-3148)
- Ning Wang (ORCID: https://orcid.org/0000-0002-9933-0725)
- Jianqiu Chen (ORCID: https://orcid.org/0000-0001-8938-1388)
- Zhilei Xie
- Leilei Lu
- Mingyu Wang (ORCID: https://orcid.org/0009-0002-9177-9509)
Institutions
- Shandong University (CN)
- China Pharmaceutical University (CN)
- Qingdao Binhai University (CN)
- Ministry of Ecology and Environment (CN)
- Inner Mongolia Electric Power Survey & Design Institute (China) (CN)
- Nanjing Institute of Environmental Sciences (CN)
- State Key Laboratory of Microbial Technology
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1093/jambio/lxaf091
- Citations
- 1
- Primary Topic
- Pharmaceutical and Antibiotic Environmental Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.50