Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)

The extraction and purification of lactic acid from fermentation processes is crucial for biotechnological product quality and productivity improvement. This mini review focuses on the topic of lactic acid purification processes that incorporate membrane separation technologies. Membrane filtration isolates lactic acid from fermentation broth without energy-intensive distillation. Membrane techniques involve microfiltration, ultrafiltration, and nanofiltration. The advantages of membrane technology are examined, including lower operational expenses, reduced thermal degradation of lactic acid, and the potential for continuous operation. This paper summarizes our research on the use of membrane separation systems, particularly microfiltration and nanofiltration, for the separation and concentration of lactic acids from fermentation broths derived from sugarcane molasses. Based on the data collected during our study, we have decided to implement membrane technology as the primary method for separation in our future work to enhance the overall efficiency and sustainability of LA production. This integration is expected to improve both the yield and purity of LA, making the production process more economically viable. Consequently, the adoption of these advanced filtration techniques could lead to a more sustainable approach in the bioprocessing industry.

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Publication Details

Journal
Results in Chemistry
Published
2025-04-18
DOI
https://doi.org/10.1016/j.rechem.2025.102280
Citations
5
Primary Topic
Extraction and Separation Processes
Type
article
Field-Weighted Citation Impact
3.57
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article

Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)

Amal R. Mansour, Irene S. Fahim, B.M. Elmowafy, Ahmed M. Omara et al.
5 citations
Results in Chemistry
Extraction and Separation Processes
3.57
article

Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review)

Amal R. Mansour, Irene S. Fahim, B.M. Elmowafy, Ahmed M. Omara, Nahla. M. Salatein, A. M. Abdelghany, Rawan K. Hassan
article en
5 citations

Abstract

The extraction and purification of lactic acid from fermentation processes is crucial for biotechnological product quality and productivity improvement. This mini review focuses on the topic of lactic acid purification processes that incorporate membrane separation technologies. Membrane filtration isolates lactic acid from fermentation broth without energy-intensive distillation. Membrane techniques involve microfiltration, ultrafiltration, and nanofiltration. The advantages of membrane technology are examined, including lower operational expenses, reduced thermal degradation of lactic acid, and the potential for continuous operation. This paper summarizes our research on the use of membrane separation systems, particularly microfiltration and nanofiltration, for the separation and concentration of lactic acids from fermentation broths derived from sugarcane molasses. Based on the data collected during our study, we have decided to implement membrane technology as the primary method for separation in our future work to enhance the overall efficiency and sustainability of LA production. This integration is expected to improve both the yield and purity of LA, making the production process more economically viable. Consequently, the adoption of these advanced filtration techniques could lead to a more sustainable approach in the bioprocessing industry.

Results in ChemistryVol. 15
National Research Centre (EG), World Health Organization - Egypt (EG), Nile University (EG)
Affordable and clean energy
Openalex Percentile: Top 8%
Extraction and Separation Processes
3.57
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Lactic acid separation technologies: Enhancing efficiency and purity using membrane separation technology (mini review) — Amal R. Mansour, Irene S. Fahim, et al. · Results in Chemistry (2025) | TGRS Research Map | TGRS