Anaplastic meningioma to supraclavicular lymph node with malignant B cell lymphoma: A rare case report

• Meningiomas account for approximately 15 % of all primary CNS tumors and are the most common extra-axial tumors. • Meningiomas are thought to metastasize distantly via spread of CSF or venous system predominantly to the lungs, pleura and liver; lymphatic spread being even more rare. • Anaplastic meningioma is accompanied by a high rate of mitosis and abundant necrosis and is characterized by intense cerebral invasion with the ability to metastasize. • Recent studies have shown promise in anti-angiogenic therapy for the patients with highly vascular and high-grade meningiomas. To date, no reported case of meningioma metastatic to the supraclavicular lymph node with concomitant CD5+ B -cell Lymphoma has been reported in the English literature. We report a modern case of 88-year-old man with recurrent anaplastic meningioma commenced on bevacizumab after failing multiple surgical resections and radiation therapy, found to have tumor dissemination to an ipsilateral supraclavicular lymph node with a unique coexistence of CD5+ B -cell Lymphoma. His disease’s key features of multiple recurrence of meningioma, surgical excisions and radiation therapy, failure on bevacizumab therapy and unique coexistence with lymphoma, are highlighted in concordance with the literature.