Diagnostic accuracy of Truenat MTB Ultima on sputum for pulmonary tuberculosis diagnosis in an HIV-endemic setting
Ultima met the minimum sensitivity recommended by the WHO for TB detection, but specificity, reagent lot variation, and unsuccessful results were suboptimal.
Authors
- Arthur Chiwaya
- Shima M. Abdulgader
- Robin M. Warren (ORCID: https://orcid.org/0000-0001-5741-7358)
- Welile V. Dube-Nwamba (ORCID: https://orcid.org/0000-0003-4231-1467)
- Desiree L Mbu
- Zaida Palmer
- Byron W P Reeve (ORCID: https://orcid.org/0000-0002-3332-3477)
- Morten Rühwald (ORCID: https://orcid.org/0000-0002-1597-441X)
- Hridesh Mishra (ORCID: https://orcid.org/0000-0002-8572-2736)
- Grant Theron (ORCID: https://orcid.org/0000-0002-9216-2415)
- Adam Penn‐Nicholson (ORCID: https://orcid.org/0000-0002-1883-0059)
- Nondumiso Lushozi
- Zola Nkwanyana
Institutions
- South African Medical Research Council (ZA)
- FIND (CH)
- Stellenbosch University (ZA)
- Centre for Global Health Research (CA)
- National Research Foundation (ZA)
Publication Details
- Journal
- Clinical Microbiology and Infection
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1016/j.cmi.2025.04.013
- Citations
- 7
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 9.77
Funders
- European Commission
- South African Medical Research Council
- National Institutes of Health