A man with chronic progressive mucositis and extensive skin detachment

A 62-year-old man was referred to our department with a 6-week history of a progressively worsening rash. Three weeks earlier, he had been admitted for gastric perforation, which was ultimately attributed to follicular lymphoma diagnosed through a lymph node evaluation. A physical examination revealed marked erosions with hemorrhagic crust in the nasal cavity, oral cavity, lips, eyes, and perianal area and widespread skin detachment throughout the body (Fig. 1A–C). Laboratory examinations revealed leukocytosis (12,200/μL), and antinuclear antibody testing was negative.