METTL16/IGF2BP2 axis enhances malignant progression and DDP resistance through up-regulating COL4A1 by mediating the m6A methylation modification of LAMA4 in hepatocellular carcinoma
METTL16 and IGF2BP2 jointly mediated the m6A methylation modification of LAMA4, thereby promoting DDP resistance and malignant progression of HCC through regulation of COL4A1.
Authors
- Wei Bi (ORCID: https://orcid.org/0000-0003-2836-9144)
- Liming Cao (ORCID: https://orcid.org/0000-0003-2836-9347)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Cell Division
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s13008-025-00152-2
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03