Metastatic Prostatic Adenocarcinoma to the Penis with Diffuse P16 Expression: Recognizing a Diagnostic Pitfall
This case emphasizes the importance of thorough clinicopathological correlation in unusual metastatic presentations and highlights that p16 overexpression, even in penile tumors, may indicate Rb1 inactivation rather than HPV-related SCC.
Authors
- Mahmut Akgül (ORCID: https://orcid.org/0000-0003-0929-0940)
- Zsombor Melegh (ORCID: https://orcid.org/0000-0001-7605-5719)
- Levente Kuthi (ORCID: https://orcid.org/0000-0001-9247-6679)
- Zsófia Kürönya (ORCID: https://orcid.org/0000-0001-8500-5924)
- Imola Adamik
- Márton Csaba Gráczia
Institutions
- Semmelweis University (HU)
- National Institute of Oncology (HU)
- Albany Medical Center Hospital (US)
Publication Details
- Journal
- Pathobiology
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1159/000545971
- Primary Topic
- Genital Health and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00