Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

We conclude that these findings inform our understanding of the dopaminergic basis of neurophysiological variability often seen in patients with PD, and indicate that our methodological approach may be useful for data-driven contextualization of medication effects on cortical neurophysiology in future research and clinical applications. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

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Institutions

Publication Details

Journal
Movement Disorders
Published
2025-04-18
DOI
https://doi.org/10.1002/mds.30200
Citations
4
Primary Topic
Neurological disorders and treatments
Type
article
Field-Weighted Citation Impact
5.56

Funders

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article

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

Mikkel C. Vinding, Per Svenningsson, Daniel Lundqvist, Josefine Waldthaler et al.
4 citations
Movement Disorders
Neurological disorders and treatments
5.56
article

Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease

Mikkel C. Vinding, Per Svenningsson, Daniel Lundqvist, Josefine Waldthaler, Panagiota Tsitsi, Alex I. Wiesman
article en
4 citations

Abstract

We conclude that these findings inform our understanding of the dopaminergic basis of neurophysiological variability often seen in patients with PD, and indicate that our methodological approach may be useful for data-driven contextualization of medication effects on cortical neurophysiology in future research and clinical applications. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Movement DisordersVol. 40(8)
University of Copenhagen (DK), Simon Fraser University (CA), Karolinska Institutet (SE)
Stiftelsen för Strategisk Forskning, Canada Research Chairs, Knut och Alice Wallenbergs Stiftelse, Stiftelsen för Strategisk Forskning, National Institutes of Health, Canadian Institutes of Health Research
Openalex Percentile: Top 4%
Neurological disorders and treatments
5.56
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