The effects of SGLT2 inhibitors and GLP-1 receptor agonists on the triglyceride to HDL cholesterol ratio and the triglyceride-glucose index in patients with type 2 diabetes
We analyzed the medical records of 100 patients with type 2 diabetes to evaluate the effects of new antidiabetic drugs on the TG/HDL-C ratio and the TG-glucose index. We found that GLP-1 RA treatment significantly improved both markers, while SGLT2 inhibitors led to significant reductions only in the latter.
Authors
- Theocharis Koufakis (ORCID: https://orcid.org/0000-0002-5853-1352)
- Ioannis Stergiou (ORCID: https://orcid.org/0009-0004-4892-7590)
- Ioanna Zografou (ORCID: https://orcid.org/0000-0002-5669-9469)
- Georgios Dimakopoulos (ORCID: https://orcid.org/0000-0002-2351-7411)
- Manfredi Rizzo (ORCID: https://orcid.org/0000-0002-9549-8504)
- Evangelos Liberopoulos (ORCID: https://orcid.org/0000-0002-7162-3323)
- Kalliopi Kotsa (ORCID: https://orcid.org/0000-0003-2376-740X)
- Dimitra Voziki
Institutions
- University of Ioannina (GR)
- National and Kapodistrian University of Athens (GR)
- Aristotle University of Thessaloniki (GR)
- AHEPA University Hospital (GR)
- General Hospital of Athens G. Genimatas (GR)
- Laiko General Hospital of Athens (GR)
- Ippokrateio General Hospital of Thessaloniki (GR)
- 424 General Military Hospital (GR)
- Hippocration General Hospital (GR)
- Ras al-Khaimah Medical and Health Sciences University (AE)
Publication Details
- Journal
- Journal of Diabetes and its Complications
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1016/j.jdiacomp.2025.109044
- Citations
- 2
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.59