Chemical reprogramming culture for the expansion of salivary gland epithelial basal progenitor cells
Our findings demonstrate that our CRC system is an effective method for the long-term culture of SG-BPCs. This advancement holds significant promise for the development of SG epithelial progenitor-based therapies to treat SG hypofunction.
Authors
- Nam Suk Sim (ORCID: https://orcid.org/0000-0002-5567-8076)
- Seung-Min Hong (ORCID: https://orcid.org/0000-0001-5488-8445)
- Ye Jin Jeong
- Jae‐Yol Lim (ORCID: https://orcid.org/0000-0002-9757-6414)
- Yongpyo Hong
- Yeo‐Jun Yoon (ORCID: https://orcid.org/0000-0002-2560-4762)
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Gangnam Severance Hospital (KR)
- Yonsei University Health System (KR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s13287-025-04295-5
- Citations
- 4
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- National Research Foundation
- Yonsei University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Commercializations Promotion Agency for R and D Outcomes
- Yonsei University College of Medicine