A COMPARATIVE ANALYSIS OF CONSERVATIVE VERSUS SURGICAL MANAGEMENT FOR PANCREATIC PSEUDOCYSTS – A RETROSPECTIVE COHORT STUDY.

Pancreatic pseudocysts are fluid-filled sacs that develop within the pancreatic tissue or the surrounding pancreatic space. They are characterized by a non-epithelialized wall composed of fibrous and granulation tissue, hence the term “pseudo” cyst. These sacs are encapsulated collections of homogeneous fluid with minimal or no necrotic tissue within them. They are filled with amylase rich fluid. Typically, pancreatic pseudocysts are well-defined and situated outside the pancreas, often in the lesser sac. About one-third of pseudocysts are located near the head of the gland, and the remaining two-thirds occur in the tail. The pathogenesis of a pseudocyst formation in chronic pancreatitis is not well understood, but it may involve acute exacerbation of underlying pancreatitis with new calculus or protein plug formation in the pancreatic ducts