Novel insights into immune-gut microbiota interactions in colorectal cancer: a Mendelian randomization study
This study provides evidence for a potential causal relationship between immune cells, gut microbiota, and CRC, highlighting the mediating role of specific gut microbiota. These findings offer new insights into the pathogenesis of CRC and may inform future therapeutic strategies.
Authors
- Dabin Liu
- Limei Wu (ORCID: https://orcid.org/0000-0002-4979-7343)
- Jiaxing Zhao (ORCID: https://orcid.org/0000-0003-4548-2026)
- Xuehui Liu (ORCID: https://orcid.org/0000-0003-2842-7404)
- Zenghui Liu (ORCID: https://orcid.org/0000-0001-7773-9995)
- Zeyu Zhou (ORCID: https://orcid.org/0009-0001-5493-9019)
- Xiaohui Zhou (ORCID: https://orcid.org/0000-0001-7907-3293)
- Qijun Chen
- Lu Kuang (ORCID: https://orcid.org/0000-0003-0541-7289)
- Shao-Guo Wu
- Huayu Yin
Institutions
- Mudanjiang Medical University (CN)
- Affiliated Hospital of Chengde Medical College (CN)
Publication Details
- Journal
- Infectious Agents and Cancer
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s13027-025-00653-3
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- Guangzhou Municipal Science and Technology Project
- Basic and Applied Basic Research Foundation of Guangdong Province