Targeted Protein Degradation: From Basic Science to Therapeutic Applications
Targeted protein degradation (TPD) is a groundbreaking approach in molecular therapeutics, enabling the selective elimination of specific proteins by leveraging the cell's own degradation machinery. In November 2024, the SMART Symposium titled "<i>Targeted Protein Degradation: from basic science to therapeutic applications</i>" offered a comprehensive communication on the cutting-edge chemical strategies and emerging clinical applications in this rapidly advancing field.
Authors
- Xiaoyu Tang (ORCID: https://orcid.org/0000-0002-7855-5984)
- Rongkun Zhu (ORCID: https://orcid.org/0000-0001-9816-2443)
- Heng Zhang (ORCID: https://orcid.org/0009-0009-8907-1799)
Institutions
- Shenzhen Bay Laboratory (CN)
Publication Details
- Journal
- ACS Chemical Biology
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1021/acschembio.5c00067
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shenzhen Bay Laboratory