The Effect of Staging Intervals on Progression-Free Survival in Registration Studies of Oncologic Drugs: A Meta-Analysis

Studies leading to the authorization of drugs to treat incurable solid tumors applying restaging intervals ≥ 8 weeks were associated with lower HRs for PFS. The potential impact of restaging intervals on the results for PFS warrants further investigation.

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Publication Details

Journal
Cancers
Published
2025-04-18
DOI
https://doi.org/10.3390/cancers17081359
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

The Effect of Staging Intervals on Progression-Free Survival in Registration Studies of Oncologic Drugs: A Meta-Analysis

Boštjan Šeruga, Roman Adam, Arnoud J. Templeton, Ariadna Tibau et al.
Cancers
Cancer Genomics and Diagnostics
article

The Effect of Staging Intervals on Progression-Free Survival in Registration Studies of Oncologic Drugs: A Meta-Analysis

Boštjan Šeruga, Roman Adam, Arnoud J. Templeton, Ariadna Tibau, Alberto Ocaña, Eitan Amir, Jonas A. Zuellig, Filomena Udry
article en

Abstract

Studies leading to the authorization of drugs to treat incurable solid tumors applying restaging intervals ≥ 8 weeks were associated with lower HRs for PFS. The potential impact of restaging intervals on the results for PFS warrants further investigation.

CancersVol. 17(8)
Universitat Autònoma de Barcelona (ES), University of Ljubljana (SI), University of Basel (CH), University of Toronto (CA), Hospital de Sant Pau (ES), Princess Margaret Cancer Centre (CA), Hospital Clínico San Carlos (ES), Institute of Oncology Ljubljana (SI), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES), St. Claraspital (CH)
Good health and well-being
Openalex Percentile: Top 91%
Cancer Genomics and Diagnostics
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