CCT8 drives colorectal cancer progression via the RPL4-MDM2-p53 axis and immune modulation
These findings underscore the oncogenic significance of CCT8 in CRC and shed light on its molecular mechanisms, paving the way for potential therapeutic applications.
Authors
- Binhui Pan (ORCID: https://orcid.org/0000-0002-7721-5697)
- Yangyang Teng (ORCID: https://orcid.org/0000-0002-3775-328X)
- Qingji Ying (ORCID: https://orcid.org/0000-0002-7099-5758)
- Xichen Li
- Hao Lin
- Yuesheng Zhu
- Daopo Lin
- Yejiao Ruan (ORCID: https://orcid.org/0000-0001-9600-189X)
- Zhenzhai Cai (ORCID: https://orcid.org/0000-0002-8259-5049)
- Jinlin Ge
- Zijian Lin
- Xuanping Xia
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Wenzhou Central Hospital (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s12920-025-02133-4
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04