Botulinum Toxin Type A: Is It Really Useful in Improving the Aesthetic Results of Extrafacial Scars? A Prospective, Randomized, Double-Blinded Study

Botulinum toxin type A did not significantly improve extrafacial scar aesthetics or reduce NLRP3 expression. However, it was associated with decreased scar-related pruritus. Further research is needed to elucidate BoNTA's potential anti-inflammatory effects on wound healing.

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Publication Details

Journal
Dermatologic Surgery
Published
2025-04-18
DOI
https://doi.org/10.1097/dss.0000000000004642
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Botulinum Toxin Type A: Is It Really Useful in Improving the Aesthetic Results of Extrafacial Scars? A Prospective, Randomized, Double-Blinded Study

Rafael Medina, Ediléia Bagatin, Diego Dias dos Santos, Cristiane Damas Gil
Dermatologic Surgery
Dermatologic Treatments and Research
article

Botulinum Toxin Type A: Is It Really Useful in Improving the Aesthetic Results of Extrafacial Scars? A Prospective, Randomized, Double-Blinded Study

Rafael Medina, Ediléia Bagatin, Diego Dias dos Santos, Cristiane Damas Gil
article en

Abstract

Botulinum toxin type A did not significantly improve extrafacial scar aesthetics or reduce NLRP3 expression. However, it was associated with decreased scar-related pruritus. Further research is needed to elucidate BoNTA's potential anti-inflammatory effects on wound healing.

Dermatologic SurgeryVol. 51(9)
Universidade Federal de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 84%
Dermatologic Treatments and Research
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