Low-grade systemic inflammation is associated with risk of psoriasis in a general population study of more than 100 000 individuals
We found that low-grade systemic inflammation, as measured by SII, NLR and CRP, was an independent risk factor for psoriasis, especially moderate-to-severe disease. These findings support the hypothesis that low-grade systemic inflammation may contribute to the pathogenesis of psoriasis rather than simply being a consequence of the disease.
Authors
- Lone Skov (ORCID: https://orcid.org/0000-0002-4784-9680)
- Charlotte Näslund‐Koch (ORCID: https://orcid.org/0000-0003-2414-3076)
- Amanda Kvist‐Hansen (ORCID: https://orcid.org/0000-0002-0390-9151)
- Camilla Jannie Kobylecki (ORCID: https://orcid.org/0000-0001-9562-2897)
- Stig E. Bojesen (ORCID: https://orcid.org/0000-0002-4061-4133)
- Signe Vedel‐Krogh (ORCID: https://orcid.org/0000-0002-0435-1110)
Institutions
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1093/bjd/ljaf147
- Citations
- 2
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- Region Hovedstaden