A dual-response fluorescent probe Rh-O-QL for simultaneous monitoring of NAD(P)H and pH during mitochondrial autophagy
Mitochondrial autophagy is closely related to abnormal NAD(P)H and pH. Here, we synthesized a dual-response fluorescent probe with high selectivity for NAD(P)H and sensitivity in the physiological pH range, for simultaneous imaging analysis of mitochondrial NAD(P)H and pH, holding potential as a novel tool for understanding mitochondria-associated diseases.
Authors
- Yongjian Ai (ORCID: https://orcid.org/0000-0003-3018-8027)
- Liandi Guan
- Qionglin Liang (ORCID: https://orcid.org/0000-0002-6750-038X)
- Wanting Hu
- Shiyu Zhang (ORCID: https://orcid.org/0009-0008-5766-6061)
Institutions
- Qingdao University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00961h
- Citations
- 4
- Primary Topic
- Molecular Sensors and Ion Detection
- Type
- article
- Field-Weighted Citation Impact
- 3.03