Chain effect of lifecourse reproductive characteristics and body fat and muscle on cardiovascular disease in women: a Mendelian randomization study
Lifecourse reproductive characteristics and fat- and muscle-related traits manifested reciprocal mediating effects on CVD, informing targeted strategies for bridging cardiovascular health inequalities in women.
Authors
- Guang Ning
- Yufang Bi (ORCID: https://orcid.org/0000-0002-4829-5915)
- Jieli Lu (ORCID: https://orcid.org/0000-0003-1317-0896)
- Mingling Chen (ORCID: https://orcid.org/0000-0001-7992-1838)
- Lijie Kong (ORCID: https://orcid.org/0000-0002-5994-3914)
- Tiange Wang (ORCID: https://orcid.org/0000-0003-0723-489X)
- Chaojie Ye (ORCID: https://orcid.org/0009-0009-7565-5048)
- Chun Dou (ORCID: https://orcid.org/0009-0005-9505-3707)
- Weiqing Wang (ORCID: https://orcid.org/0000-0001-6027-3084)
- Dong Liu (ORCID: https://orcid.org/0000-0002-2880-4989)
- Mian Li (ORCID: https://orcid.org/0000-0001-6514-2729)
- Zhiyun Zhao
- Zheng Zhu (ORCID: https://orcid.org/0000-0001-7154-9146)
- Yu Xu (ORCID: https://orcid.org/0000-0003-1498-8331)
- Jie Zheng (ORCID: https://orcid.org/0000-0002-4265-6695)
- Min Xu (ORCID: https://orcid.org/0000-0001-9455-9494)
- Yuhong Chen
Institutions
- Shanghai Jiao Tong University (CN)
- National Health and Family Planning Commission (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s12933-025-02681-0
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Natural Science Foundation of China
- Shanghai Municipal Education Commission
- Shanghai Jiao Tong University
- National Science and Technology Major Project
- School of Medicine, Shanghai Jiao Tong University