Constructing and Interpreting Logistic Regression Analyses in Orthopedic Clinical Research

Retrospective cohort analyses are a common study design in orthopaedic clinical research given their feasibility. Nevertheless, this study design is subject to inherent biases caused by confounding variables. Logistic regression analyses are important statistical tools that can be used to clarify relationships between independent and binary dependent variables. The purpose of this paper is to provide a broad overview of logistic regression analyses and guide the interpretation of these analyses in orthopaedic clinical research.