Impact of diabetes and glycemic status on ventricular–arterial coupling in the general population
This study demonstrates a significant association between DM and impaired VAC, as reflected by elevated PWV/GLS, while no such link was observed in prediabetes. The transition from prediabetes to DM appears critical for VAC deterioration. Additionally, higher HbA1c and fP-glucose levels, even in non-diabetic individuals, were associated with worsened VAC, highlighting the impact of glycemic control on vascular function.
Authors
- Amra Jujić (ORCID: https://orcid.org/0000-0002-9506-0158)
- Gunnar Engström (ORCID: https://orcid.org/0000-0002-8618-9152)
- Peter M. Nilsson (ORCID: https://orcid.org/0000-0002-5652-8459)
- Martin Magnusson (ORCID: https://orcid.org/0000-0003-1710-5936)
- Labs-Göran Johnsson
- Carl Johan Östgren (ORCID: https://orcid.org/0000-0003-1617-3179)
- Jan Engvall (ORCID: https://orcid.org/0000-0002-5716-5098)
- Hannes Holm (ORCID: https://orcid.org/0000-0002-5419-765X)
- David Kylhammar
- Haris Zilic (ORCID: https://orcid.org/0009-0005-6100-0463)
Institutions
- Linköping University (SE)
- Lund University (SE)
- Skåne University Hospital (SE)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s12933-025-02731-7
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lunds Universitet
- Knut och Alice Wallenbergs Stiftelse