Pregnancy with a prosthetic heart valve, thrombosis, and bleeding: the ESC EORP Registry of Pregnancy and Cardiac disease III
More favourable outcomes were found in women with a biological valve compared with a mechanical valve. In women with a mechanical valve, the use of LMWH was associated with an increased risk of thromboembolic complications. A mitral prosthetic valve was identified as a predictor for valve thrombosis. The benefit could not be confirmed nor refuted, in terms of reduced thromboembolic events, from using anti-Xa level monitoring in women on LMWH.
Authors
- Catherine M Otto (ORCID: https://orcid.org/0000-0002-0527-9392)
- Jolien W. Roos‐Hesselink (ORCID: https://orcid.org/0000-0002-6770-3830)
- G. Justin Paul (ORCID: https://orcid.org/0000-0002-8588-5594)
- Johanna A van der Zande (ORCID: https://orcid.org/0000-0002-9569-6551)
- R Vasallo Peraza (ORCID: https://orcid.org/0000-0001-7026-427X)
- Karen S Sliwa (ORCID: https://orcid.org/0000-0002-8272-0911)
- Ariane J. Marelli (ORCID: https://orcid.org/0000-0002-1784-8206)
- Isabelle Malhamé (ORCID: https://orcid.org/0000-0002-9140-8735)
- Hasan Al Farhan
- Karishma P. Ramlakhan (ORCID: https://orcid.org/0000-0002-6741-2603)
- Jerome M J Cornette (ORCID: https://orcid.org/0000-0001-8482-5138)
- Aldo P. Maggioni (ORCID: https://orcid.org/0000-0003-2764-6779)
- Roger Hall
- Mark R. Johnson (ORCID: https://orcid.org/0000-0002-1625-6997)
Institutions
- University of East Anglia (GB)
- University of Baghdad (IQ)
- University of Cape Town (ZA)
- Madras Medical College (IN)
- University of Washington (US)
- Baghdad Medical City (IQ)
- McGill University Health Centre (CA)
- Erasmus MC (NL)
- Associazione Nazionale Medici Cardiologi Ospedalieri (IT)
- Havana Research Institute (US)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Imperial College London (GB)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1093/eurheartj/ehaf265
- Citations
- 15
- Primary Topic
- Cardiovascular Issues in Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 20.82
Funders
- Amgen
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- Bayer
- Sanofi
- Boston Scientific Corporation
- ResMed
- Gedeon Richter
- Stichting Zabawas
- Servier
- Novartis Pharma
- Abbott Vascular
- Daiichi Sankyo Europe