Sex differences in outcomes and time to treatment in stroke patients treated with tenecteplase

In our study, we did not find a significant difference between women and men in terms of 3-month good outcome. However, our study size may hinder its detection. Interestingly, we observed that women had a lower rate of sICH after tenecteplase. Women's workflow metrics were similar to men's, except for a higher rate of stroke with an unknown onset.

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Publication Details

Journal
European Stroke Journal
Published
2025-06-25
DOI
https://doi.org/10.1177/23969873251332497
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Sex differences in outcomes and time to treatment in stroke patients treated with tenecteplase

Pierre Seners, Didier Smadja, Nicolas Chausson, Guillaume Turc et al.
European Stroke Journal
Acute Ischemic Stroke Management
article

Sex differences in outcomes and time to treatment in stroke patients treated with tenecteplase

Pierre Seners, Didier Smadja, Nicolas Chausson, Guillaume Turc, Édouard Januel, Emmanuel Wiener, Gaspard Gerschenfeld, Gaultier Marnat, Stéphane Olindo, Sonia Alamowitch, Wagih Ben Hassen, Thomas Checkouri, Fernando Pico, Michel Piotin, Frédéric Clarençon, Marion Yger, Jildaz Caroff
article en

Abstract

In our study, we did not find a significant difference between women and men in terms of 3-month good outcome. However, our study size may hinder its detection. Interestingly, we observed that women had a lower rate of sICH after tenecteplase. Women's workflow metrics were similar to men's, except for a higher rate of stroke with an unknown onset.

European Stroke JournalVol. 10(4)
Inserm (FR), Université Paris Cité (FR), Université Paris-Saclay (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre Hospitalier Sud Francilien (FR), Pitié-Salpêtrière Hospital (FR), Fondation de Rothschild (FR), Institut de Psychiatrie et Neurosciences de Paris (FR), Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR), FHU Neurovasc (FR), Institut du Cerveau (FR), Centre Hospitalier de Versailles (FR), Bicêtre Hospital (FR)
Agence Nationale de la Recherche
Good health and well-being
Openalex Percentile: Top 88%
Acute Ischemic Stroke Management
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