Laboratory Diagnosis and Molecular Epidemiological Characterization of the First Imported Case of Lassa Fever in China.
The case was confirmed through nucleotide detection, with no evidence of secondary transmission or viral spread. The LASV strain identified belongs to lineage IV, with broader GPC variability than previously reported. Mutations in the immune-related sites of GPC may affect immune responses, necessitating heightened vigilance regarding the virus.
Authors
- Ming Pan (ORCID: https://orcid.org/0000-0002-8072-4548)
- Xiao Rong Yang
- Lü Tian (ORCID: https://orcid.org/0000-0002-5893-0169)
- Xianfeng Zhou (ORCID: https://orcid.org/0000-0002-7756-9460)
- Ming Jiang (ORCID: https://orcid.org/0000-0002-1661-0538)
- Jiandong Li (ORCID: https://orcid.org/0000-0002-5593-050X)
- Can Luo
- Wei Li (ORCID: https://orcid.org/0000-0003-4143-8597)
- Guo Chen (ORCID: https://orcid.org/0000-0003-2840-8879)
- Zhenhua Chen (ORCID: https://orcid.org/0000-0002-5195-2234)
- Hua Zhong (ORCID: https://orcid.org/0000-0001-9604-4523)
- Wei-Chen Wu (ORCID: https://orcid.org/0009-0005-8064-2023)
- Yu Feng (ORCID: https://orcid.org/0000-0001-8659-9592)
- Ren Yuan
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- National Institute for Viral Disease Control and Prevention (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-20
- DOI
- https://doi.org/10.3967/bes2025.014
- Citations
- 2
- Primary Topic
- Viral Infections and Outbreaks Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79