Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Parkinson's Disease: Results from a Phase <scp>II</scp> Randomized Control Trial (<scp>STRIPE</scp>)
No difference was seen between active and sham arms. Symptom improvements seen in both groups are consistent with a placebo effect, however, we cannot exclude a biological effect from the sham intervention. Although negative, this result should be taken only in context of Geko use rather TTNS in general. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Anisha Cullen (ORCID: https://orcid.org/0000-0001-9133-9808)
- Marcus J. Drake (ORCID: https://orcid.org/0000-0002-6230-2552)
- Yoav Ben‐Shlomo (ORCID: https://orcid.org/0000-0001-6648-3007)
- Anahita Nodehi (ORCID: https://orcid.org/0000-0001-8094-2978)
- Emily J. Henderson (ORCID: https://orcid.org/0000-0002-0016-1870)
- Matthew D. Smith (ORCID: https://orcid.org/0000-0002-4685-375X)
- Gabriella E. Portlock
Institutions
- North Bristol NHS Trust (GB)
- University of Bristol (GB)
- Royal United Hospital Bath NHS Trust (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1002/mds.30186
- Citations
- 1
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 1.84
Funders
- John Templeton Foundation
- Wellcome Trust
- Alzheimer's Society
- National Institute for Health and Care Research
- Parkinson's UK
- Gatsby Charitable Foundation
- British Geriatrics Society
- University of Oxford
- Rosetrees Trust
- University of Bristol
- Versus Arthritis
- Directorate for Biological Sciences
- Medical Research Council