Effects of electroconvulsive therapy on serum brain derived neurotrophic factor, serum interleukin-6, and serum cortisol levels in patients with treatment refractory schizophrenia
ECT reduces symptom severity in TRS, with significant modulation of IL-6 and potential involvement of BDNF in positive symptom improvement. These findings highlight immune and neuroplastic pathways as mechanisms of ECT efficacy and suggest biomarkers for treatment response.
Authors
- Ashish Sharma (ORCID: https://orcid.org/0000-0002-3716-6202)
- Nikhil Gurjar
- Jitendra Jeenger
- Devendra Mohan Mathur
Institutions
- Rabindranath Tagore Medical College (IN)
- Rajasthan Police Academy (IN)
Publication Details
- Journal
- Industrial Psychiatry Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.4103/ipj.ipj_422_24
- Citations
- 1
- Primary Topic
- Electroconvulsive Therapy Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47