Rabies virus large protein-derived T-cell immunogen facilitates rapid viral clearance and enhances protection against lethal challenge in mice
Our study suggested that combining the T-cell immunogen and virus-neutralizing antibody immunogen was a practical approach to strengthening the defense against the rabies virus.
Authors
- Cuisong Zhu (ORCID: https://orcid.org/0000-0003-3659-1466)
- Jianqing Xu (ORCID: https://orcid.org/0000-0003-0896-9273)
- Meiqi Feng (ORCID: https://orcid.org/0000-0001-8628-6094)
- Nan Gao (ORCID: https://orcid.org/0000-0003-0259-3316)
- Xinghao Pan (ORCID: https://orcid.org/0009-0001-6400-4399)
- Ai Xia (ORCID: https://orcid.org/0000-0003-0373-9196)
- Shimeng Bai (ORCID: https://orcid.org/0000-0003-4020-1934)
- Xiaoyan Zhang (ORCID: https://orcid.org/0000-0002-3193-1401)
- Miaomiao Zhang (ORCID: https://orcid.org/0000-0003-4657-5320)
- Tianhan Yang
Institutions
- Fudan University (CN)
- Southern University of Science and Technology (CN)
- Shanghai Public Health Clinical Center (CN)
- Zhongshan Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1038/s43856-025-00851-5
- Citations
- 4
- Primary Topic
- Rabies epidemiology and control
- Type
- article
- Field-Weighted Citation Impact
- 4.15
Funders
- National Natural Science Foundation of China
- Science and Technology Commission of Shanghai Municipality