Italian Consensus on the treatment of oral lichen planus

Oral lichen planus (OLP) is a chronic inflammatory condition of uncertain etiology affecting oral mucosae by T-cell mediated chronic inflammation. It affects between 1% and 3% of the global population, predominantly middle-aged adults (50-60 years), with a higher incidence in women. The immune response is thought to target keratinocytes, leading to cell death, particularly through CD8+ T lymphocytes. OLP manifests in various clinical forms, such as reticular, papular, erosive, and atrophic, with the reticular subtype being the most common. Erosive OLP is the most severe, characterized by widespread oral erosions, while atrophic OLP often follows erosive stages, affecting the tongue with a depapillated surface. Currently, no curative treatment exists for OLP, and the management focuses on symptom relief, including reducing pain and discomfort. Thus, a multidisciplinary approach involving dermatologists, oral surgeons, and dentists is often required. For this reason, the scientific community represented in Italy by the Mucosal Diseases Study Group of SIDeMaST (Italian Society of Dermatology and Venereology) reports its experience in the management of OLP, providing clinical recommendations for dermatologists based on the latest scientific evidence to optimize the treatment and management of OLP.

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Publication Details

Journal
Italian Journal of Dermatology and Venereology
Published
2025-04-01
DOI
https://doi.org/10.23736/s2784-8671.25.08143-5
Citations
2
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
2.93
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article

Italian Consensus on the treatment of oral lichen planus

Martina D’Onghia, Emanuele Cozzani, Andrea Gabusi, Laura Calabrese et al.
2 citations
Italian Journal of Dermatology and Venereology
Oral Health Pathology and Treatment
2.93
article

Italian Consensus on the treatment of oral lichen planus

Martina D’Onghia, Emanuele Cozzani, Andrea Gabusi, Laura Calabrese, Federica Filippi, Stefano Piaserico, Giulia Gasparini, Oriana Simonetti, Manuela PAPINI, Alessandro Borghi, Anna Maria Offidani, Federico Bardazzi, Élisa Cinotti, Giulia Galluccio, Jacopo Tartaglia, Pietro Rubegni, Aurora Parodi, Monica Corazza
article en
2 citations

Abstract

Oral lichen planus (OLP) is a chronic inflammatory condition of uncertain etiology affecting oral mucosae by T-cell mediated chronic inflammation. It affects between 1% and 3% of the global population, predominantly middle-aged adults (50-60 years), with a higher incidence in women. The immune response is thought to target keratinocytes, leading to cell death, particularly through CD8+ T lymphocytes. OLP manifests in various clinical forms, such as reticular, papular, erosive, and atrophic, with the reticular subtype being the most common. Erosive OLP is the most severe, characterized by widespread oral erosions, while atrophic OLP often follows erosive stages, affecting the tongue with a depapillated surface. Currently, no curative treatment exists for OLP, and the management focuses on symptom relief, including reducing pain and discomfort. Thus, a multidisciplinary approach involving dermatologists, oral surgeons, and dentists is often required. For this reason, the scientific community represented in Italy by the Mucosal Diseases Study Group of SIDeMaST (Italian Society of Dermatology and Venereology) reports its experience in the management of OLP, providing clinical recommendations for dermatologists based on the latest scientific evidence to optimize the treatment and management of OLP.

Italian Journal of Dermatology and VenereologyVol. 160(2)
University of Siena (IT), Università Cattolica del Sacro Cuore (IT), Marche Polytechnic University (IT), University of Padua (IT), University of Ferrara (IT), University of Perugia (IT), Martin University (US), Istituto delle Scienze Neurologiche di Bologna (IT), Ospedale Policlinico San Martino (IT), University of Bologna (IT)
Zero hunger
Openalex Percentile: Top 11%
Oral Health Pathology and Treatment
2.93
DOISourceOpenAlex
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