Validation of the Zwolle Risk Score in STEMI Patients Undergoing Primary PCI: Insights from the ISCAS-STEMI COVID-19 Registry

This study is the first to demonstrate the good prognostic performance of the ZRS in a large-scale contemporary global multicenter validation set. Similar results were obtained both in the pre-pandemic and the COVID-19 era. ZRS ≤3 identified a very low-risk population that could be discharged early, even during the COVID-19 pandemic, with expected advantages in the availability of hospital beds and nursing staff, costs of medical care, and in-hospital risk of contagion.

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Publication Details

Journal
Current Vascular Pharmacology
Published
2025-04-18
DOI
https://doi.org/10.2174/0115701611335913250408214530
Primary Topic
COVID-19 and healthcare impacts
Type
article
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article

Validation of the Zwolle Risk Score in STEMI Patients Undergoing Primary PCI: Insights from the ISCAS-STEMI COVID-19 Registry

Hélder Pereira, Rui Campante Teles, Elvin Kedhi, Alev Arat Özkan et al.
Current Vascular Pharmacology
COVID-19 and healthcare impacts
article

Validation of the Zwolle Risk Score in STEMI Patients Undergoing Primary PCI: Insights from the ISCAS-STEMI COVID-19 Registry

Hélder Pereira, Rui Campante Teles, Elvin Kedhi, Alev Arat Özkan, Veauthyelau Saint Joy, Xacobe Flores‐Ríos, Luca Donazzan, Magdy Algowhary, Jurriën M. ten Berg, Michael Lee, Alexandre Schaan de Quadros, Michał Kidawa, Zan Zimbakov, Lucia Marinucci, Antonia Anna Lukito, Gustavo Pessah, Benjamin Faurie, Adriaan O. Kraaijeveld, Tomáš Kovárník, C. Uribe, Poay Huan Loh, Filippo Zilio, Árpád Lux, Hsien‐Li Kao, Gabriele Gabrielli, V. I. Ganyukov, Fortunato Scotto di Uccio, Ylitalo Antti, Matteo Nardin, И. С. Бессонов, Christos Mantis, John Kanakakis, Giuliana Cortese, Rodrigo Zoni, Dafsah Arifa Juzar, Heidi Lehtola, Vincenzo Guiducci, Víctor Manuel Becerra‐Muñoz, Luigi Vignali, Dinaldo Cavalcanti de Oliveira, Maurizio Menichelli, Alessandra Scoccia, Kadir Uğur Mert, Francesco Versaci, Petr Kala, Gianluca Caiazzo, Lisette Okkels Jensen, Lucian Câlmâc, Rodrigo de Moura Joaquim, Gianni Casella, Monica Verdoia, Pablo Lamelas, Aylin Hatice Yamaç, Bruno Scheller, Nikola Bakraceski, Enrico Fabris, Guido Parodi, Flavien Vincent, Gennaro Galasso, Giuseppe Cirrincione, Stephane Manzo-Silbermann, Davor Miličić, Santiago Ordóñez, Dimitrios Alexopulos, Maurits T. Dirksen, João Silveira, Miha Čerček, Carlos Arellano Serrano, Periklis A. Davlouros, Íñigo Lozano, Aaron Wong Sung Lung, George Kochiadakis, Alejandro Gutiérrez, Juan Sanchís, Stefano Savonitto, José Luis Díez Gil, José Moreu, Harry Suryapranata, Alfredo Rodriguez, Alex Rocha, Francisco Bosa Ojeda, Roberto Paladino, Clemens von Birgelen, Gerard Roura Ferrer, Berat Uğuz, Frankie Chor-Cheung Tam, Marco Boccalatte, Xavier Carillo, Mohammed Abed Burgadha, Marek Malewski, Jaun Pablo Bachini
article en

Abstract

This study is the first to demonstrate the good prognostic performance of the ZRS in a large-scale contemporary global multicenter validation set. Similar results were obtained both in the pre-pandemic and the COVID-19 era. ZRS ≤3 identified a very low-risk population that could be discharged early, even during the COVID-19 pandemic, with expected advantages in the availability of hospital beds and nursing staff, costs of medical care, and in-hospital risk of contagion.

Current Vascular PharmacologyVol. 24(1)
Pelita Harapan University (ID), University of Messina (IT), Université Libre de Bruxelles (BE), University of Padua (IT), University Hospital Centre Zagreb (HR), Radboud University Nijmegen (NL), Inserm (FR), Medical University of Silesia (PL), University of Zagreb (HR), Bursa Technical University (TR), Université Paris Cité (FR), Masaryk University (CZ), Universidade Federal de Pernambuco (BR), Oulu University Hospital (FI), Clinical Emergency Hospital Bucharest (RO), Maastricht University Medical Centre (NL), Hospital Universitario de Canarias (ES), Queen Mary Hospital (CN), Ljubljana University Medical Centre (SI), Odense University Hospital (DK), General University Hospital of Patras (GR), Medisch Spectrum Twente (NL), Bellvitge University Hospital (ES), Radboud University Medical Center (NL), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), University of Indonesia (ID), University Medical Center Utrecht (NL), Centre Hospitalier Universitaire de Lille (FR), Hospital Universitari i Politècnic La Fe (ES), University of Tyumen (RU), Bezmiâlem Vakıf Üniversitesi (TR), Accademia di Belle Arti di Frosinone (IT), Maastricht University (NL), Ospedale Maggiore (IT), Ospedale Santa Chiara (IT), Azienda Sanitaria Unità Locale di Reggio Emilia (IT), Ospedale di Bolzano (IT), Ospedale degli Infermi (IT), Hospital Clínico Universitario de Valencia (ES), Assistance Publique – Hôpitaux de Paris (FR), Ospedale Maggiore Carlo Alberto Pizzardi (IT), Northwest Hospital (US), University Hospital Brno (CZ), Istituto Clinico Sant'Ambrogio (IT), St. Antonius Ziekenhuis (NL), Turku PET Centre (FI), Hospital Universitario Puerta de Hierro Majadahonda (ES), Azienda Ospedaliero Universitaria di Sassari (IT), Azienda Ospedaliero Universitaria Ospedali Riuniti (IT), Azienda Ospedaliera S.Giuseppe Moscati (IT), Groupe Hospitalier Mutualiste de Grenoble (FR), Fundação Universitária de Cardiologia (BR), Alessandro Manzoni Hospital (IT), Alexandra Hospital (GR), Ospedale Santa Maria (IT), Ospedali Riuniti Marche Nord (IT), Medical University of Lodz (PL), Hospital de Santa Cruz (PT), Assiut University Hospitals (EG), Hospital de Santo António (PT), National Taiwan University Hospital (TW), Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona (IT), Ospedale di Parma (IT), Instituto Nacional de Investigación Agropecuaria (UY), Pembuluh Darah Harapan Kita (ID), Instituto de Cardiologia de Santa Catarina (BR), University Hospital of Heraklion (GR), Azienda Ospedaliera Universitaria Policlinico "G. Martino" (IT), Servicio Diabetología Hospital Córdoba (AR), University General Hospital Attikon (GR), Ospedale Santa Maria Goretti (IT), Complexo Hospitalario Universitario A Coruña (ES), Hospital Universitario Puerta del Mar (ES), Azienda di Rilievo Nazionale ed Alta Specializzazione (IT), National University Hospital (SG), Hospital Garcia de Orta (PT), National Heart Centre Singapore (SG), Sanatorio Otamendi y Miroli (AR), Ospedale Sant'Anna (IT), Clínica CES (CO), Hospital Universitario De Cabueñes (ES), Ospedale degli Infermi (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Hospital Universitari Germans Trias i Pujol (ES), Agia Olga Hospital (GR), Sociedad Española de Cardiología (ES), Hospital Clínico Universitario Virgen de la Victoria (ES), Medisch Centrum Alkmaar (NL), Instituto Cardiovascular de Buenos Aires (AR), General University Hospital in Prague (CZ), Complejo Hospitalario Universitario de Toledo (ES), Azienda Sanitaria Universitaria Integrata di Trieste (IT), Queen Elizabeth Hospital (CN), Marqueurs cardiovasculaires en situation de stress (FR), Eskişehir Osmangazi University (TR), Kemerovo State University (RU), Istanbul University (TR), Ss. Cyril and Methodius University in Skopje (MK), University of Blida (DZ), University of Hong Kong (HK), Assiut University (EG), Saarland University (DE), University of Twente (NL)
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COVID-19 and healthcare impacts
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