Diagnostic MicroRNA Signatures to Support Classification of Pulmonary Hypertension
We suggest a threshold for NT-proBNP to identify patients with a high probability of PH, and the subsequent use of circulating miRNA signatures to help differentiate PH subgroups.
Authors
- Luke Howard (ORCID: https://orcid.org/0000-0003-2822-210X)
- Yiu-Lian Fong
- David Gerard Kiely (ORCID: https://orcid.org/0000-0003-0184-6502)
- Eileen M. Harder (ORCID: https://orcid.org/0000-0003-1085-6024)
- Aaron B. Waxman (ORCID: https://orcid.org/0000-0001-7797-0361)
- Lihan Zhou (ORCID: https://orcid.org/0000-0002-1096-2604)
- Christopher J. Rhodes (ORCID: https://orcid.org/0000-0002-4962-3204)
- Mark R. Toshner (ORCID: https://orcid.org/0000-0002-3969-6143)
- Dennis Wang (ORCID: https://orcid.org/0000-0003-0068-1005)
- Niamh Errington
- John Wharton (ORCID: https://orcid.org/0000-0001-8110-2575)
- Robin Condliffe (ORCID: https://orcid.org/0000-0002-3492-4143)
- A. A. Roger Thompson (ORCID: https://orcid.org/0000-0002-0717-4551)
- Allan Lawrie (ORCID: https://orcid.org/0000-0003-4192-9505)
- Sokratis Kariotis
- Martin R. Wilkins (ORCID: https://orcid.org/0000-0003-3926-1171)
- Cheng He (ORCID: https://orcid.org/0000-0002-8102-8245)
- Li Zhou
- T. Jatkoe
Institutions
- Agency for Science, Technology and Research (SG)
- Brigham and Women's Hospital (US)
- Johnson & Johnson (United States) (US)
- Imperial College Healthcare NHS Trust (GB)
- University of Cambridge (GB)
- Cambridge School (PT)
- Lung Institute (US)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- Papworth Hospital NHS Foundation Trust (GB)
- Zhoushan Hospital (CN)
- University of Sheffield (GB)
Publication Details
- Journal
- Circulation Genomic and Precision Medicine
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1161/circgen.124.004862
- Citations
- 7
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 10.63
Funders
- Imperial College London
- Actelion Pharmaceuticals