Determination of individual intolerance or sensitivity to dental materials: a comprehensive approach, rationale

Background. The main purpose of the study is to develop a unified test method for determining individual sensitivity to dental materials used in prosthetic dentistry. Given the current state of dental science and the development of new materials, there is a need to create a methodology that will allow early detection of patients with hypersensitivity to certain materials. This is important to ensure high quality dental services and avoid negative reactions to dental materials. This test method allows identifying patients who may have a negative reaction to certain materials and take this into account when choosing materials for prosthetics. The development of a unified test method will help reduce the incidence of implant rejection and gum inflammation, as well as improve the clinical outcomes of prosthetics in patients. The use of such a test in clinical practice will allow dentists to make a more informed choice of materials, which in turn will increase the effectiveness of treatment and patient satisfaction. The article is devoted to the important problem of individual tolerance of structural materials in dentistry. The study emphasizes that different patients may have different sensitivities to the same materials used for prosthetics. This emphasizes the need for a personalized approach in dental practice, where the choice of materials is based on the individual characteristics of the patient. During a series of clinical and laboratory studies of individual tolerance to denture materials, it was found that in the clinic of prosthetic dentistry, individual intolerance to certain materials is often observed. This phenomenon is due to the complex biological and chemical composition of materials that can interact with body tissues. Identification of such cases allows timely adjustment of the choice of materials and avoidance of negative consequences for patients. When using the tests, the muco-gingival test (MGT) is preferred due to its high objectivity and ease of use. This approach allows for a comprehensive assessment of patientsʼ reactions to materials and determines the most convenient and effective methods for diagnosing intolerance to dental structures. Due to its simplicity andaccuracy, the MGT is becoming an indispensable tool in the work of a dentist, reducing risks and improving the quality of services provided. The study also confirms that all materials, including ceramics, can cause individual intolerance with various clinical symptoms. This may include inflammation, allergic reactions, and other negative manifestations that affect the patientʼs overall health. Therefore, it is important to conduct a careful selection of materials, taking into account the individual characteristics of each patient. This emphasizes the importance of improving the methods for determining the tolerance of materials to improve the quality of dental prosthetics and ensure patient comfort. The use of new technologies and diagnostic methods will significantly improve treatment outcomes and increase patient confidence in dental services. Thus, the implementation of the developed test method will be an important step in the development of prosthetic dentistry and improving the quality of life of patients. Purpose – is to develop a unified test method for determining individual sensitivity to dental materials used in prosthetic dentistry. Materials and Methods. In the study, two groups of patients were tested using four independent well-known tests that have been previously used to determine individual intolerance in dental practice. These tests included two laboratory tests, the peroxidase test and the interleukin test, and two contact tests. The use of these four tests allowed us to obtain a complete picture of individual sensitivity to dental materials in the study groups of patients. Only those patients who had undergone a thorough examination of the oral cavity and prosthetic structures were taken into account. After that, it was established that no medical errors were made during the treatment process. Results. Provocative tests are an important step in identifying components that can cause intolerance in patients using metal-ceramic structures. Taking into account the data obtained, it can be concluded that the MGT is the most optimal in such cases. This test is convenient and fairly objective, as it combines laboratory and clinical parts of the study. This approach allows for a comprehensive assessment of patientsʼ reactions to materials and determination of the most convenient and effective methods for diagnosing intolerance to dental structures. Conclusions. During a series of clinical and laboratory studies of individual intolerance to denture materials, it was found that in the clinic of prosthetic dentistry, individual intolerance to certain materials is frequently observed. The MGT proved to be the most effective being highly objective and easy to use. It is important to note that all materials, including ceramics, can cause individual intolerance with different clinical symptoms. This emphasizes the importance of a detailed analysis and evaluation of the patientʼs interaction with denture materials to avoid negative reactions and achieve successful treatment.