Heme Oxygenase-1 Modulates Macrophage Polarization Through Endothelial Exosomal miR-184-3p and Reduces Sepsis-Induce Lung Injury
Collectively, we elucidated a novel potential therapeutic mechanism that HO-1 alleviate inflammation by modulating the M1/M2 ratio in sepsis-induced ALI by regulating miR-184-3p/Sema7a expression.
Authors
- Jianbo Yu (ORCID: https://orcid.org/0000-0002-8674-4435)
- Zhuo Du (ORCID: https://orcid.org/0000-0002-6322-4656)
- Xiaoyang Wu (ORCID: https://orcid.org/0000-0001-6378-3207)
- Yi-Bo Yang
- Ya Wu (ORCID: https://orcid.org/0000-0002-8131-994X)
- Jinkun Chen (ORCID: https://orcid.org/0009-0008-1846-2162)
- Wei Chen (ORCID: https://orcid.org/0000-0001-6959-7122)
- Shuan Dong (ORCID: https://orcid.org/0000-0002-5344-2342)
- Yuan Zhang (ORCID: https://orcid.org/0000-0002-5019-8911)
- Lirong Gong (ORCID: https://orcid.org/0000-0002-4528-3484)
Institutions
- Tianjin University (CN)
- Tianjin Nankai Hospital (CN)
- Integrative Medicine Institute (US)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s506830
- Citations
- 7
- Primary Topic
- Thermal Regulation in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 10.82