Association between gynecological cancers and female infertility: insights from bidirectional Mendelian randomization analysis

Our study found no significant causal relationship between FI and GC. However, a potential marginal association between BC and FI was observed. These findings underscore the need for further research to confirm this association and emphasize the importance of reproductive protection for young breast cancer patients to preserve fertility.

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Publication Details

Journal
BMC Women s Health
Published
2025-04-18
DOI
https://doi.org/10.1186/s12905-025-03729-9
Citations
1
Primary Topic
Genetic and phenotypic traits in livestock
Type
article
Field-Weighted Citation Impact
1.82
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article

Association between gynecological cancers and female infertility: insights from bidirectional Mendelian randomization analysis

Yifei Zeng, Dongxiao Zhang, Jifeng Li
1 citations
BMC Women s Health
Genetic and phenotypic traits in livestock
1.82
article

Association between gynecological cancers and female infertility: insights from bidirectional Mendelian randomization analysis

Yifei Zeng, Dongxiao Zhang, Jifeng Li
article en
1 citations

Abstract

Our study found no significant causal relationship between FI and GC. However, a potential marginal association between BC and FI was observed. These findings underscore the need for further research to confirm this association and emphasize the importance of reproductive protection for young breast cancer patients to preserve fertility.

BMC Women s HealthVol. 25(1)
Capital Medical University (CN), Beijing Hospital of Traditional Chinese Medicine (CN)
Gender equality
Openalex Percentile: Top 17%
Genetic and phenotypic traits in livestock
1.82
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