Identifying Causal Brain Structures, Genes, and Proteins for Osteoarthritis: A Large-Scale Genetic Correlation Study Based on Brain Imaging-Derived Phenotypes, Transcriptomes, and Proteomes
This study enhances our understanding of the brain-joint axis in OA genetics, potentially informing new treatment strategies and therapeutic targets.
Authors
- Yong Zhu (ORCID: https://orcid.org/0000-0002-4069-2481)
- Haitao Long
- Ruibo Zhao (ORCID: https://orcid.org/0000-0002-1225-3051)
- Zhe Ruan (ORCID: https://orcid.org/0000-0002-8190-4022)
- Chao Wang (ORCID: https://orcid.org/0000-0001-5399-0157)
- Zhi Liu (ORCID: https://orcid.org/0000-0001-8292-4562)
- Zhangyuan Lin
- Wenfeng Xiao (ORCID: https://orcid.org/0000-0003-0515-3113)
- Shushan Zhao
- Yusheng Li
Institutions
- Central South University (CN)
- National Clinical Research (US)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1093/gerona/glaf083
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00