Crystal Shape Factors of Form I Paracetamol

In this work, we report the new protocols that are developed to determine the shape factors of Form I paracetamol crystals using a combination of techniques that rely on the state-of-the-art X-ray computed tomography and Morphologi G3. The determined shape factors successfully predicted the crystal growth rate of paracetamol in 2-propanol and the length of the crystals growing in the supersaturated solution.

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Publication Details

Journal
Crystal Growth & Design
Published
2025-04-18
DOI
https://doi.org/10.1021/acs.cgd.5c00005
Citations
1
Primary Topic
Crystallization and Solubility Studies
Type
article
Field-Weighted Citation Impact
0.52

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article

Crystal Shape Factors of Form I Paracetamol

K. Vasanth Kumar, Mahmoud Ranjbar, Jun‐Tao Li, Mayank Vashishtha et al.
1 citations
Crystal Growth & Design
Crystallization and Solubility Studies
0.52
article

Crystal Shape Factors of Form I Paracetamol

K. Vasanth Kumar, Mahmoud Ranjbar, Jun‐Tao Li, Mayank Vashishtha, Paul Robert Shearing, Srinivas Gadipelli, Gavin Walker
article en
1 citations

Abstract

In this work, we report the new protocols that are developed to determine the shape factors of Form I paracetamol crystals using a combination of techniques that rely on the state-of-the-art X-ray computed tomography and Morphologi G3. The determined shape factors successfully predicted the crystal growth rate of paracetamol in 2-propanol and the length of the crystals growing in the supersaturated solution.

Crystal Growth & DesignVol. 25(9)
University of Limerick (IE), University of Surrey (GB), University of Oxford (GB), Physical Sciences (United States) (US), Chemical Synthesis Lab (SG), University College London (GB)
Boston Scientific Corporation, Science Foundation Ireland, Bernal Institute, University of Limerick
Zero hunger
Openalex Percentile: Top 40%
Crystallization and Solubility Studies
0.52
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Crystal Shape Factors of Form I Paracetamol — K. Vasanth Kumar, Mahmoud Ranjbar, et al. · Crystal Growth & Design (2025) | TGRS Research Map | TGRS