TO STUDY THE CLINICAL PROFILE OF RENAL INVOLVEMENT IN GASTROENTERITIS PATIENTS BY LABORATORY STUDIES.

Introduction Acute Kidney Injury (AKI) is a sudden loss of kidney function, often triggered by conditions such as acute gastroenteritis (AGE). AGE, characterized by diarrhea and dehydration, is a significant cause of prerenal AKI, particularly in developing countries. Severe dehydration from AGE can lead to hypovolemia, electrolyte imbalances, and renal dysfunction, increasing morbidity and mortality. Despite its clinical significance, there is limited research on the biochemical and clinical markers that predict AKI in AGE patients, necessitating further investigation. Objectives This study aims to evaluate the clinical profile of renal involvement in AGE patients. Methods This prospective observational study was conducted at Saraswathi Institute of Medical Sciences, Hapur, over two years (2023–2025). Patients diagnosed with AKI following AGE were enrolled, with AKI classified using KDIGO criteria. Biochemical markers such as serum creatinine, blood urea nitrogen, and electrolytes were analyzed. Clinical parameters, dehydration severity, and treatment outcomes were assessed statistically to identify key risk factors for AKI development and prognosis. ResultThe study analyzed 100 gastroenteritis patients diagnosed with AKI, identifying severe diarrhea, dehydration, and oliguria as key risk factors. Serum creatinine emerged as a reliable AKI marker. Early rehydration significantly improved renal outcomes. Males and younger patients (18-43 years) were at higher risk. Comorbidities such as diabetes worsened prognosis. Findings highlight the necessity of early detection, fluid management, and routine renal monitoring to prevent complications. Future research should explore long-term outcomes and additional biochemical markers. Conclusion This study highlights the importance of early detection, timely fluid management, and comprehensive monitoring of renal function in gastroenteritis patients. Targeted interventions can significantly improve patient outcomes and prevent long-term kidney complications.