The Changing Impact of Human Cytomegalovirus Serology and Infection on Patient Outcome After Allogeneic Hematopoietic Stem Cell Transplantation: An Italian Prospective Multicenter Survey in the Era of Letermovir Prophylaxis
In patients who received LET-PP, recipient/donor serology no longer correlates with early CS-HCMV-i whereas it still predicts late CS-HCMV-i as well as risk of CS-HCMV-i in patients who did not receive LET-PP. Donor serology, CS-HCMV-i and HCMV disease no longer impact survival in allo-HSCT recipients who receive LET-PP. <b>Clinical Trials Registration</b>. NCT04412811.
Authors
- Corrado Girmenia (ORCID: https://orcid.org/0000-0002-3245-2357)
- Ilaria Cutini
- Angelo Michele Carella (ORCID: https://orcid.org/0000-0002-4967-4204)
- Raffaella Greco (ORCID: https://orcid.org/0000-0002-6117-5328)
- Tiziana Lazzarotto (ORCID: https://orcid.org/0000-0003-3093-363X)
- Luca Castagna (ORCID: https://orcid.org/0000-0002-6239-7387)
- Alessandra Carotti
- Alessandra Picardi (ORCID: https://orcid.org/0000-0002-0136-7686)
- Fabio Ciceri (ORCID: https://orcid.org/0000-0003-0873-0123)
- Michele Malagola (ORCID: https://orcid.org/0000-0003-0907-130X)
- Giovanni Marsili
- A. Rinaldi (ORCID: https://orcid.org/0000-0002-8211-5076)
- Massimo Martino
- Maria Caterina Micò (ORCID: https://orcid.org/0009-0006-6931-4632)
- Alessandro Busca (ORCID: https://orcid.org/0000-0001-5361-5613)
- Fausto Baldanti (ORCID: https://orcid.org/0000-0002-3358-8969)
- Alfonso Piciocchi (ORCID: https://orcid.org/0000-0001-8648-885X)
- Elisabetta Terruzzi
- Patrizia Chiusolo (ORCID: https://orcid.org/0000-0002-1355-1587)
- Stéfania Bramanti (ORCID: https://orcid.org/0000-0002-4117-7991)
- Maura Faraci (ORCID: https://orcid.org/0000-0001-5715-501X)
- Gaetana Porto (ORCID: https://orcid.org/0000-0003-4739-349X)
- Francesco Onida (ORCID: https://orcid.org/0000-0002-2991-3474)
- Francesca Bonifazi (ORCID: https://orcid.org/0000-0003-1544-9911)
- Irene Cavattoni
- Federica Galaverna (ORCID: https://orcid.org/0000-0003-0717-2924)
- Adriana Vacca
- Roberto Bono (ORCID: https://orcid.org/0000-0002-2471-6594)
- Pierangelo Clerici
- Anna Paola Iori
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Rome Tor Vergata (IT)
- University of Pavia (IT)
- Casa Sollievo della Sofferenza (IT)
- Policlinico Umberto I (IT)
- Istituto Giannina Gaslini (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Ospedale Maggiore (IT)
- Azienda Ospedaliera di Perugia (IT)
- Ospedale di Bolzano (IT)
- Azienda ospedaliera "Bianchi-Melacrino-Morelli" (IT)
- Ospedale Vincenzo Cervello (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Ospedale Papa Giovanni XXIII (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Istituto di Ematologia di Bologna (IT)
- Azienda USL di Bologna (IT)
- Presidio Ospedaliero (IT)
- Bambino Gesù Children's Hospital (IT)
- Ospedale di Parma (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- ASST Fatebenefratelli Sacco (IT)
- University of Brescia (IT)
- Sapienza University of Rome (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1093/ofid/ofaf233
- Citations
- 2
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 2.71