Profiling the resistome and virulome of Bacillus strains used for probiotic-based sanitation: a multicenter WGS analysis
The data obtained by metagenomic analysis revealed the absence of genetic sequences associated with PBS-Bacillus and the lack of alterations in all the environmental isolates analyzed, despite their continuous contact with surrounding pathogens. These results support the safety of the Bacillus species analyzed. Further metagenomic studies aimed at profiling the whole genomes of these and other species of Bacillus, possibly during longer periods and under stress conditions, would be of interest since they may provide further confirmation of their stability and safety.
Authors
- Silvia Argimón (ORCID: https://orcid.org/0000-0002-2884-3857)
- Elisabetta Caselli (ORCID: https://orcid.org/0000-0001-6048-9141)
- Eleonora Mazziga
- Antonella Volta (ORCID: https://orcid.org/0000-0002-5350-1592)
- Sophia David (ORCID: https://orcid.org/0000-0002-0115-0954)
- Maria D’Accolti (ORCID: https://orcid.org/0000-0003-1937-5534)
- Francesca Bini
- David M. Aanensen (ORCID: https://orcid.org/0000-0001-6688-0854)
- Matteo Bisi (ORCID: https://orcid.org/0000-0002-2478-7894)
- Irene Soffritti
- Sante Mazzacane (ORCID: https://orcid.org/0000-0002-9018-7600)
- Julio Diaz Caballero (ORCID: https://orcid.org/0000-0003-4664-8577)
Institutions
- University of Ferrara (IT)
- University of Oxford (GB)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s12864-025-11582-1
- Citations
- 7
- Primary Topic
- Bacillus and Francisella bacterial research
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Bill and Melinda Gates Foundation