Do cell culturing influence the radiosensitizing effect of gold nanoparticles: a Monte Carlo study
Our results indicate that the direction of irradiation plays a crucial role in determining the effectiveness of AuNPs in reducing SF. Furthermore, the results suggest that using cells in suspension will reduce the dependence of cell survival on the beam direction during irradiation, regardless of the radiation quality used.
Authors
- Inês A. Marques (ORCID: https://orcid.org/0000-0001-5690-3020)
- J. Antunes
- Teresa Pinheiro (ORCID: https://orcid.org/0000-0002-1836-2603)
- Ana Belchior (ORCID: https://orcid.org/0000-0002-6010-0316)
- Maria Filomena Botelho (ORCID: https://orcid.org/0000-0001-7202-1650)
- J.M. Sampaio (ORCID: https://orcid.org/0000-0003-4359-493X)
- S. Pires
Institutions
- Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento (PT)
- University of Lisbon (PT)
- LIP - Laboratory of Instrumentation and Experimental Particle Physics (PT)
- Institute for Biotechnology and Bioengineering (PT)
- University of Coimbra (PT)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1186/s40658-025-00746-3
- Citations
- 2
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 3.04