Primary Gastrointestinal <scp>EBV</scp>‐Associated Classical Hodgkin Lymphoma in Crohn Disease on Anti‐<scp>TNF</scp>‐α Therapy: A Rare Association

Primary intestinal CHL comprises less than 5% of gastrointestinal lymphomas; CHL arising in the context of Crohn disease is even more rare. Most lymphomas associated with inflammatory bowel disease and/or immunosuppression are non-Hodgkin type. In this case, the long-term treatment with anti-TNF-α and EBV positivity suggested an iatrogenic immunodeficiency-associated lymphoma, an emerging group of lymphoproliferative disorders associated with the increased use of immunosuppressants.

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Publication Details

Journal
JGH Open
Published
2025-04-01
DOI
https://doi.org/10.1002/jgh3.70154
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Primary Gastrointestinal EBV‐Associated Classical Hodgkin Lymphoma in Crohn Disease on Anti‐TNF‐α Therapy: A Rare Association

Nishi Dave, Ani Toklu, Hector Mesa, Katrina Collins
JGH Open
Lymphoma Diagnosis and Treatment
article

Primary Gastrointestinal EBV‐Associated Classical Hodgkin Lymphoma in Crohn Disease on Anti‐TNF‐α Therapy: A Rare Association

Nishi Dave, Ani Toklu, Hector Mesa, Katrina Collins
article en

Abstract

Primary intestinal CHL comprises less than 5% of gastrointestinal lymphomas; CHL arising in the context of Crohn disease is even more rare. Most lymphomas associated with inflammatory bowel disease and/or immunosuppression are non-Hodgkin type. In this case, the long-term treatment with anti-TNF-α and EBV positivity suggested an iatrogenic immunodeficiency-associated lymphoma, an emerging group of lymphoproliferative disorders associated with the increased use of immunosuppressants.

JGH OpenVol. 9(4)
University of Maryland, Baltimore (US), University of Maryland Medical Center (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Good health and well-being
Openalex Percentile: Top 89%
Lymphoma Diagnosis and Treatment
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