Increased Uptake of 68Ga-DOTA-IBA in Lung NUT Carcinoma

Nuclear protein in testis gene rearrangement-associated midline carcinoma (NUT carcinoma) is a rare and highly invasive tumor. Here, we are reporting the image findings of a 38-year-old woman with lung NUT carcinoma. To evaluate the bone metastases, she underwent 68 Ga-labeled DOTA-ibandronic acid ( 68 Ga-DOTA-IBA) PET/CT examination. Surprisingly, the patient's lung primary focus and subcutaneous nodule on the left side of the lower back region showed increased uptake.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-04-18
DOI
https://doi.org/10.1097/rlu.0000000000005902
Primary Topic
Protein Degradation and Inhibitors
Type
article
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0.00
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article

Increased Uptake of 68Ga-DOTA-IBA in Lung NUT Carcinoma

Huipan Liu, Na Zhang, Yue Chen, Linwei Li et al.
Clinical Nuclear Medicine
Protein Degradation and Inhibitors
article

Increased Uptake of 68Ga-DOTA-IBA in Lung NUT Carcinoma

Huipan Liu, Na Zhang, Yue Chen, Linwei Li, Tingting Xu
article en

Abstract

Nuclear protein in testis gene rearrangement-associated midline carcinoma (NUT carcinoma) is a rare and highly invasive tumor. Here, we are reporting the image findings of a 38-year-old woman with lung NUT carcinoma. To evaluate the bone metastases, she underwent 68 Ga-labeled DOTA-ibandronic acid ( 68 Ga-DOTA-IBA) PET/CT examination. Surprisingly, the patient's lung primary focus and subcutaneous nodule on the left side of the lower back region showed increased uptake.

Clinical Nuclear MedicineVol. 50(11)
Target (United States) (US), Southwest Medical University (CN), Affiliated Hospital of Southwest Medical University (CN)
Good health and well-being
Openalex Percentile: Top 93%
Protein Degradation and Inhibitors
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