Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS

The peptide level immunocapture LC-MS/MS analysis eliminated the interference of anti-BCMA biotherapeutics, allowing for the quantification of total sBCMA in clinical samples while achieving a LLOQ of 10 ng/mL.

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Publication Details

Journal
Journal of Mass Spectrometry and Advances in the Clinical Lab
Published
2025-04-01
DOI
https://doi.org/10.1016/j.jmsacl.2025.04.006
Citations
2
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
2.72
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article

Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS

Alexandra Tavernier, Johanna Paris, Sylvie Bethegnies, Olivier Fedeli et al.
2 citations
Journal of Mass Spectrometry and Advances in the Clinical Lab
Monoclonal and Polyclonal Antibodies Research
2.72
article

Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS

Alexandra Tavernier, Johanna Paris, Sylvie Bethegnies, Olivier Fedeli, Sandrine Descloux
article en
2 citations

Abstract

The peptide level immunocapture LC-MS/MS analysis eliminated the interference of anti-BCMA biotherapeutics, allowing for the quantification of total sBCMA in clinical samples while achieving a LLOQ of 10 ng/mL.

Journal of Mass Spectrometry and Advances in the Clinical LabVol. 36
Sanofi (France) (FR)
Zero hunger
Openalex Percentile: Top 11%
Monoclonal and Polyclonal Antibodies Research
2.72
DOIOpen Access PDFOpenAlex
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Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS — Alexandra Tavernier, Johanna Paris, et al. · Journal of Mass Spectrometry and Advances in the Clinical Lab (2025) | TGRS Research Map | TGRS