Deciphering the Risk of Developing Lung Cancer after the Diagnosis of Gastric Cancer with Genetic Evidence: A European and East Asian Populations–Based Mendelian Randomization Analysis
This study confirms that genetic susceptibility to gastric cancer increases the risk of lung cancer. This finding provides a theoretical basis for exploring the underlying biological mechanisms and suggests that enhancing lung cancer screening in patients with gastric cancer may be necessary to improve patient prognosis.
Authors
- Zhong-shan Yang
- Linda M. Liao (ORCID: https://orcid.org/0000-0002-1923-5294)
- Siwei Huang (ORCID: https://orcid.org/0000-0001-8409-1330)
- Sida Sun (ORCID: https://orcid.org/0000-0001-8580-7433)
- Weijie Wu (ORCID: https://orcid.org/0000-0002-4894-5981)
- Ai‐Ming Zeng
- Junfeng Zhou (ORCID: https://orcid.org/0000-0003-0954-6598)
- Jiansheng Chen (ORCID: https://orcid.org/0000-0002-2040-7938)
- Yunzhe Yu
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
- Putian University (CN)
- Fuzhou University (CN)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-04-18
- DOI
- https://doi.org/10.4143/crt.2024.875
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council