Association of CALLY index and CLR with COPD risk in middle-aged and older Americans: evidence from NHANES 2017–2020
The study identifies a linear negative relationship between the CALLY index and COPD, unaffected by potential confounders. A higher CLR is linked to an elevated risk of COPD development. Both the CALLY index and CLR were superior in predicting the risk of developing COPD. Our findings emphasize that the CALLY index and CLR may be a new inflammatory early warning biomarker for COPD.
Authors
- Wenyi Du (ORCID: https://orcid.org/0000-0002-8649-7796)
- He Huang (ORCID: https://orcid.org/0000-0002-6223-4799)
- Leyan Chen (ORCID: https://orcid.org/0009-0001-6414-6258)
- Jian Zhou (ORCID: https://orcid.org/0000-0003-4736-9457)
- Mingfeng Zheng
- Yuhao Chen (ORCID: https://orcid.org/0009-0003-0576-4712)
Institutions
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-04-17
- DOI
- https://doi.org/10.3389/fmed.2025.1535415
- Citations
- 8
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 12.15