Dark seasons enhance brain and brown adipose tissue interactions related to mu-opioid receptor signaling
These findings suggest that shorter photoperiods enhance, while longer photoperiods reduce, the predictability of brain MOR levels on BAT MOR signaling. These data imply that darker seasons may amplify the interaction between brain activity and peripheral physiology associated with MOR signaling. The adaptability of brain-BAT interactions under stress stimuli offers a new avenue for exploring systems biology.
Authors
- Anne Roivainen (ORCID: https://orcid.org/0000-0002-4006-7977)
- Anne Marlene Landau (ORCID: https://orcid.org/0000-0002-7371-8713)
- Lihua Sun (ORCID: https://orcid.org/0000-0002-9931-9497)
- Jing Tang (ORCID: https://orcid.org/0000-0001-7480-7710)
Institutions
- University of Helsinki (FI)
- University of Turku (FI)
- Turku Centre for Computer Science (FI)
- Aarhus University (DK)
- Helsinki Institute of Physics (FI)
- Turku University Hospital (FI)
- Aarhus University Hospital (DK)
- Turku PET Centre (FI)
- Huashan Hospital (CN)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1007/s00259-025-07272-5
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Turun Yliopisto