Cardiovascular disease risk in patients with psoriasis receiving biologics targeting TNF-α, IL-12/23, IL-17, and IL-23: A population-based retrospective cohort study

Patients with psoriasis prescribed biologics exhibited a lower risk of CVDs versus those on oral therapy. Anti-TNF-α, anti-IL-17, and anti-IL-23 were associated with decreased cardiovascular hazards, while anti-IL-12/23 was not.

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Publication Details

Journal
PLoS Medicine
Published
2025-04-17
DOI
https://doi.org/10.1371/journal.pmed.1004591
Citations
16
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
12.76

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article

Cardiovascular disease risk in patients with psoriasis receiving biologics targeting TNF-α, IL-12/23, IL-17, and IL-23: A population-based retrospective cohort study

Teng‐Li Lin, Chao-Kuei Juan, Yi‐Hsuan Fan, Chun-Ying Wu et al.
16 citations
PLoS Medicine
Psoriasis: Treatment and Pathogenesis
12.76
article

Cardiovascular disease risk in patients with psoriasis receiving biologics targeting TNF-α, IL-12/23, IL-17, and IL-23: A population-based retrospective cohort study

Teng‐Li Lin, Chao-Kuei Juan, Yi‐Hsuan Fan, Chun-Ying Wu, Kuo-Sheng Fan
article en
16 citations

Abstract

Patients with psoriasis prescribed biologics exhibited a lower risk of CVDs versus those on oral therapy. Anti-TNF-α, anti-IL-17, and anti-IL-23 were associated with decreased cardiovascular hazards, while anti-IL-12/23 was not.

PLoS MedicineVol. 22(4)
National Yang Ming Chiao Tung University (TW), National Chung Hsing University (TW), China Medical University (TW), Taipei Veterans General Hospital (TW), Taichung Veterans General Hospital (TW), Chung Shan Medical University Hospital (TW)
Taichung Veterans General Hospital
Good health and well-being
Openalex Percentile: Top 1%
Psoriasis: Treatment and Pathogenesis
12.76
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