Acyclovir-induced Nephrotoxicity: Protective Potential of N-acetylcysteine

Oxidative stress could be a key process in acyclovir (ACV)-induced nephrotoxicity. N-acetylcysteine (NAC) is a water-soluble antioxidant with anti-inflammatory activity. This study aimed to evaluate the protective effect of NAC on ACV-induced nephrotoxicity in adult Wistar rats.

Authors

Publication Details

Journal
Journal of Exploratory Research in Pharmacology
Published
2025-03-25
DOI
https://doi.org/10.14218/jerp.2024.00037
Citations
1
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
1.32
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article

Acyclovir-induced Nephrotoxicity: Protective Potential of N-acetylcysteine

Bonsome Bokolo, Tobechı Brendan Nnanna, James Kemelayefa, Elias Adikwu
1 citations
Journal of Exploratory Research in Pharmacology
Hepatitis C virus research
1.32
article

Acyclovir-induced Nephrotoxicity: Protective Potential of N-acetylcysteine

Bonsome Bokolo, Tobechı Brendan Nnanna, James Kemelayefa, Elias Adikwu
article en
1 citations

Abstract

Oxidative stress could be a key process in acyclovir (ACV)-induced nephrotoxicity. N-acetylcysteine (NAC) is a water-soluble antioxidant with anti-inflammatory activity. This study aimed to evaluate the protective effect of NAC on ACV-induced nephrotoxicity in adult Wistar rats.

Journal of Exploratory Research in PharmacologyVol. 10(1)
Zero hunger
Openalex Percentile: Top 22%
Hepatitis C virus research
1.32
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Acyclovir-induced Nephrotoxicity: Protective Potential of N-acetylcysteine — Bonsome Bokolo, Tobechı Brendan Nnanna, et al. · Journal of Exploratory Research in Pharmacology (2025) | TGRS Research Map | TGRS